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mavorixafor will improve the degree or impact of codeine by influencing hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a powerful CYP2D6 inhibitor) is contraindicated with prescription drugs which might be highly dependent on CYP2D6 for clearance.There might be other Negative effects of dextromethorphan that are not listed here. Ca